DNA damage can occur during normal cellular processes or when exposed to external environments. there are several types of DNA damage, including single strand breaks (SSB), double strand breaks (DSB), base damage and cross-linking of DNA strands. DNA damage can lead to mutations, chromosomal aberrations and even cell death, and is a hallmark of various diseases. Therefore, cells have evolved multiple DNA repair mechanisms to counteract DNA damage and maintain genomic integrity. One of these mechanisms is homologous recombination repair (HRR), a complex DNA repair mechanism that corrects DSBs in DNA. Defects in the HRR pathway are associated with a variety of human diseases, including cancer and genetic disorders such as Fanconi anemia.
CD Genomics offers reliable HRR reference products to help you analyze mutations in genes involved in the HRR pathway in cancer.
Our HRR reference products contain a variety of mutations associated with the HRR pathway, such as:
Our technical team can customize gDNA, ctDNA, and FFPE for the above mutations, which are widely used for the registration of HRR test kits and daily quality control of HRR tests.
Our HRR reference products are derived from cell lines close to clinical samples.
Explore Our Homologous Recombination Repair (HRR) Reference Products:
|CD HRR Reference
|CD HRR Reference contains mutations related to the HRR pathway and can be customized in the form of gDNA, ctDNA or FFPE, which are ideal reference products for HRR test kit registration and daily quality control of HRR tests.