Minimal Residual Disease (MRD) Reference Products

Current Status of MRD Research

Minimal Residual Disease MRD Reference Products

Minimal residual diseases (MRD) are small amounts of cancer cells that may remain in a patient's body after treatment. MRD testing is studied in leukemia, lymphoma, and solid tumors. MRD testing is usually performed by advanced technologies such as flow cytometry, PCR-based assays, or next-generation sequencing to detect circulating tumor DNA (ctDNA) in the blood or microscopic tumor cells in the bone marrow of cancer patients. It is widely used for monitoring the efficacy of cancer patients, assessing the risk of recurrence, evaluating prognosis and making decisions about therapeutic interventions.

CD Genomics offers reliable MRD reference products to help you conduct solid tumor (lung, colorectal, breast, prostate, etc.) studies to further guide treatment decisions and assess patients' risk of recurrence.

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Minimal Residual Disease (MRD) Reference Products Details

MRD testing in solid tumors is challenging due to the large individual variation in solid tumors and the extremely low levels of ctDNA released into peripheral blood from early stage tumors. We develop accurate MRD reference products for process performance validation and routine quality control of MRD laboratory testing programs. These reference products require the highest level of NGS panel design and sensitivity for MRD detection.

Origin

Our MRD reference products are derived from 100% cell lines.

Product Highlights

Coverage of common tumor targeting therapy-related genes, including multiple hotspot mutations and tumor-associated mutations.
Digital PCR for accurate quantification.
NGS MRD panel is highly consistent with digital PCR validation results.
Gradient mutation frequency to meet the detection limit validation needs of MRD lab testing program flow.
Validation by lllumina TruSight Oncology 500 ctDNA panel, providing validation results for user reference.
Consistent and reliable quality.

Applications

Our MRD reference products are widely used in MRD labs for process performance validation and daily quality control.

* For Research Use Only. Not for use in diagnostic procedures.

Explore Our Minimal Residual Disease (MRD) Reference Products:

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Cat. No.	Product Name	Brief Description	Inquiry	Basket
CTRM012	CD ctDNA MRD RM Mix	Our ctDNA MRD RM Mix is a highly precise reference material, supporting the detection of mutations in cancer-related cells and liquid biopsies. Our product provides multiple allele frequency options, including 0%, 0.005%, 0.05%, 0.5%.
MRDR001	CD Tumor Micro-Residue Lesion Detection ctDNA Quality Control Kit	To facilitate the clinical application and promotion of the MRD LDT process for solid tumors, CD has developed a ctDNA quality control product suitable for performance validation and daily quality control of the MRD LDT process.