HPV Genotyping Detection Panels

Brief Introduction

Cervical cancer is the fourth most common cancer in women worldwide, and almost all cervical cancers are associated with persistent infection with one of the high-risk human papillomaviruses (high-risk HPV). Approximately 200 reference HPV types are listed in the Papillomavirus Awareness (PaVE) database, and more than 40 HPV types have been identified to have high tropism for mucosal epithelia, with at least 12 HPV subtypes classified as high-risk by International Agency for Research on Cancer (IARC). Of these, HPV16 and HPV18 subtypes account for approximately 70% of cases. Not all HPVs have the same risk of cancer development, so genotyping testing for HPV types can provide valuable information for preclinical and clinical studies, including identification of multiple HPV infections, pathogenesis studies, epidemiological studies, and drug development. Genome detection and DNA amplification assays are widely used for comprehensive HPV subspecies detection and identification.

Our HPV PCR Genotyping Detection Kits

Our HPV PCR panels, designed for high and low-risk HPV types, contain specific primers and fluorescent probes, and non-competitive internal controls. They significantly improve the accuracy and reproducibility of assay verification and validation.

Product Name	Cat. No.	Size	Features
CD 14 High Risk HPV Multiplex Real-time PCR Kit	PM003	1 kit	Multiplex Real-time PCR; Detection of HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68; Differentiate between HPV16 (ROX) and HPV18 (VIC) and other HPV genotypes (FAM); Top sensitivity of 100 copies/rxn; High sensitivity and specificity: >90%
CD 15 High-Risk Human Papillomavirus (HPV) Real-time PCR Kit	PM174	1 kit	Real-Time Qualitative PCR; Detection of 15 types of High-risk HPV Genotypes (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, 82) in genital swabs, cervical cells and paraffin section samples; Top sensitivity: 1×10⁴ copies/ml

Our HPV Target Enrichment Panels

Our HPV Capture Panels are designed to rapidly capture 201 HPV strains and simplify the process of library preparation for the identification and analysis of HPV subtypes and novel variants, as well as integration sites. Based on the HPV genomic database, our ready-to-use target enrichment panels improve the coverage and sequencing analysis of the entire HPV genome, gaining uniform and unbiased sequencing data, and reducing time and sequencing costs.

Product Name	Cat. No.	Size	Features
CDCAP® HPV Capture Kit	PN008	16/96	Hybridization capture; High specificity and sensitivity; Fast and streamlined workflow; Analysis of HPV subtypes, mutations, and integration sites.

Targeted HPV Types

Unspecified HPV Types, 30, 34, 39, 40, 53, 57, 59, 61, 62, 64, 66, 67, 68, 69

Low-risk HPV Types, 6, 11, 16, 18, 31, 33, 35, 42, 43, 44, 45, 51, 52, 74

High-risk HPV Types, 16, 18, 6, 11, 31, 34, 33, 35, 39, 42, 44, 45, 51, 52, 56, 58, 66

Workflow for Target Enrichment Panel

Our NGS Panel kits generate high-quality sequencing libraries in less than two days, for hybridization capture or amplification prior to next-generation sequencing. They improve library conversion efficiency while reducing workflow complexity and hands-on time.

Workflow