Details
| Product Infomation | |
|---|---|
| Product Description: | The CD PIK3CA mutation analysis kit can be used to detect PIK3CA somatic mutations based on probe-based real-time PCR technology. PIK3CA mutations are genetic alterations that affect the PI3K/AKT/mTOR signaling pathway, which plays a critical role in regulating cell growth, survival, and proliferation. These mutations are commonly found in many types of cancer, including breast, colorectal, ovarian, endometrial, and lung cancer. |
| Features: | Mutation: E542K, E545K, E545Q, H1047L, H1047R Mutation Name Nucleotide Change E542K c.1624G>A E545K c.1633G>A E545Q c.1633G>C H1047L c.3140A>T H1047R c.3140A>G |
| Sequencing Platform: | Real-time PCR |
| Storage: | Store in < -20℃ freezer. Repeated thawing and freezing should be avoided. |
| Method: | Real-time qualitative PCR |
| Equipment Required: | Real-time PCR instrument (FAM and VIC) |
| Required Reagents: | DNA extraction kit, pipettors and filter tips |
| ShippingCondition: | Dry ice |
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